R. E. Austic G. L. Rumsey Y. N. Chiu 1984 <p></p><p>1. Rainbow trout fingerlings were fed diets containing 1.2, 1.8 and 2.6% histidine and two mixtures of Na, K and Cl (<i>Na</i> + <i>K</i> - <i>C</i><i>l</i> = 0 <i>or</i> -200 <i>meq</i>/<i>kg</i><i>diet</i>) in a factorial design.</p><p>2. Growth and efficiency of feed conversion were not affected by histidine in the diet when it contained the −200 meq/kg electrolyte mixture, but with the 0 meq/kg level, 2.6% histidine depressed both measures of response.</p><p>3. Histidine increased plasma and muscle histidine levels, increased hepatic histidase activity, but did not affect hepatic histidine-pyruvate aminotransferase activity.</p><p>4. Muscle-free histidine concentrations were markedly higher and lysine concentrations were lower in trout receiving 0 meq/kg than those receiving the −200 meq/kg electrolyte mixture.</p><p>5. The electrolyte balance of the diet has a marked effect on the metabolism of histidine in trout.</p><p></p> application/pdf 10.1016/0305-0491(84)90187-1 en Elsevier Effect of dietary electrolytes and histidine on histidine metabolism and acid-base balance in rainbow trout (<i>Salmo gairdneri</i>) article