<?xml version='1.0' encoding='utf-8'?>
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:contributor>B.S. Roberson</dc:contributor>
  <dc:contributor>O. W. Dixon</dc:contributor>
  <dc:creator>D. P. Anderson</dc:creator>
  <dc:date>1979</dc:date>
  <dc:description>&lt;p&gt;&lt;span&gt;Splenic antibody-producing cells were produced by rainbow trout that had been exposed to O-antigens extracted from&amp;nbsp;&lt;/span&gt;&lt;i&gt;Yersinia ruckeri&lt;/i&gt;&lt;span&gt;&amp;nbsp;and&amp;nbsp;&lt;/span&gt;&lt;i&gt;Aeromonas salmonicida&lt;/i&gt;&lt;span&gt;&amp;nbsp;by adding the concentrated antigen preparation directly into the water of the tank holding the fish for a flush exposure. This method was compared with the proven techniques of exposure: intraperitoneal injection or a 2 minute immersion of the fish in the antigen preparation. Dosage experiments showed that the production of antibody-producing cells was induced by the immersion of trout for 2 minutes in water with 5.0 μg/ml-1 (or more) with the&amp;nbsp;&lt;/span&gt;&lt;i&gt;Y. ruckeri&lt;/i&gt;&lt;span&gt;&amp;nbsp;O-antigen, or 500 μg ml-1 (or more) of the&amp;nbsp;&lt;/span&gt;&lt;i&gt;A. salmonicida&lt;/i&gt;&lt;span&gt;&amp;nbsp;O-antigen. Similar differences were evident when the respective antigens were added directly to the water.&lt;/span&gt;&lt;/p&gt;</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>10.1111/j.1095-8649.1979.tb03611.x</dc:identifier>
  <dc:language>en</dc:language>
  <dc:publisher>Wiley</dc:publisher>
  <dc:title>Induction of antibody-producing cells in rainbow trout, Salmo gairdneri Richardson, by flush exposure</dc:title>
  <dc:type>article</dc:type>
</oai_dc:dc>