D. L. Dawe
S. W. Pyle
1985
<p>Experiments were conducted to measure the agglutinating antibody response of channel catfish to a particulate and a soluble antigen administered simultaneously by one of three routes. Specific antibody production in response to administration of particulate brucella tube-test antigen via intramuscular injection, oral drench, and topical application peaked at 3 weeks in channel catfish held under identical conditions at 21°C. The humoral antibody response was greater in fish injected with antigen than in the orally or topically exposed channel catfish.</p><p>Specific antibody was also produced by the same channel catfish in response to the administration of a soluble ciliary preparation derived from<span> </span><i>Tetrahymena pyriformis</i><span> </span>Lwoff. Intramuscular injection of<span> </span><i>Tetrahymena</i><span> </span>antigen was the only route that produced detectable levels of circulating antibody as measured by direct agglutination of live<span> </span><i>T. pyriformis</i><span> </span>cells. The response to the soluble antigen also peaked at 3 weeks.</p><p>Neither antigen elicited detectable agglutinins in cutaneous mucus, regardless of the vaccination method used.</p>
application/pdf
10.1016/0044-8486(85)90169-3
en
Elsevier
Immune response of channel catfish, Ictalurus punctatus Rafinesque, to bacterial and protozoan antigens administered by three routes
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