W. L. Shelton N. C. Parker C. A. Goudie 1986 <div id="preview-section-abstract"><div id="abstracts" class="Abstracts u-font-gulliver text-s"><div id="aep-abstract-id5" class="abstract author"><div id="aep-abstract-sec-id6"><p>Radioactivity levels in 10 tissues were monitored for 21 days after adult (1-year-old) blue tilapia,<span>&nbsp;</span><i>Oreochromis aureus</i>, were fed a single meal of a diet containing 30 μg unlabelled methyltestosterone (MT) per gram of feed and radiolabelled MT (³H-labelled steroid nucleus and<span>&nbsp;</span>¹⁴C-labelled 17α-methyl group). Radioactivity was highest in all tissues 6–12 h after the feeding; about 90% of the radioactivity was in the digestive tract, liver, gall bladder, and kidney. Radioactivity declined nearly 90% by 4 days and only 0.5% of original radioactivity (67 ng/g of fish) remained after 21 days. Half of the remaining exogenous hormone was in digestive and excretory tissues; concentrations in muscle were less than 1 ng/g of tissue. Ratios of<span>&nbsp;</span>³H:¹⁴C in tissues were similar to those incorporated in the diet and suggested that the 17α-methyl group was not removed during metabolism.</p></div></div></div></div> application/pdf 10.1016/0044-8486(86)90088-8 en Elsevier Tissue distribution and elimination of radiolabelled methyltestosterone fed to adult blue tilapia article