Colleen A. Caldwell
Bill Olsen
Dave Serdar
Mike Coffey
Christopher J. Schmitt
2002
<p><span>We assessed the effects on fish of lead (Pb) released to streamsby smelters located in Trail, BC (Canada), E. Helena, MT, Herculaneum, MO, and Glover, MO. Fish were collected by electrofishing from sites located downstream of smelters and from reference sites. Blood from each fish was analyzed for δ-aminolevulinic acid dehydratase (</span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=ALAD&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">ALAD</a><span>) activity and hemoglobin (Hb), and samples of blood, liver, or carcass were analyzed for Pb, zinc (Zn), or both. Fish collected downstreamof all four smelters sites had elevated Pb concentrations, decreased </span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=ALAD&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">ALAD</a><span> activity, or both relative to their respectivereference sites. At E. Helena, fish from the downstream site also had lower Hb concentrations than fish from upstream. Differences among taxa were also apparent. Consistent with previous studies, </span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=ALAD&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">ALAD</a><span> activity in catostomids (</span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=Pisces&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">Pisces</a><span>: Catostomidae-northern hog sucker,</span><i class="a-plus-plus">Hypentelium nigricans</i><span>;river carpsucker, </span><i class="a-plus-plus">Carpiodes carpio</i><span>; largescale sucker, </span><i class="a-plus-plus">Catostomus macrocheilus</i><span>; and mountain sucker, </span><i class="a-plus-plus">C. platyrhynchus</i><span>) seemed more sensitive to Pb-induced </span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=ALAD&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">ALAD</a><span>inhibition than the salmonids (</span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=Pisces&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">Pisces</a><span>: Salmonidae-rainbow trout,</span><i class="a-plus-plus">Oncorhynchus mykiss</i><span>; brook trout,</span><i class="a-plus-plus">Salvelinus fontinalis</i><span>) or common carp (</span><i class="a-plus-plus">Cyprinus carpio</i><span>). Some of these differences may have resulted from differential accumulation of Zn, which was not measured at all sites. We detected no</span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=ALAD&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">ALAD</a><span> activity in channel catfish (</span><i class="a-plus-plus">Ictaluruspunctatus</i><span>) from either site on the Mississippi River at Herculaneum, MO. Our findings confirmed that Pb is releasedto aquatic ecosystems by smelters and accumulated by fish, andwe documented potentially adverse effects of Pb in fish. We recommend that Zn be measured along with Pb when </span><a class="reference-link webtrekk-track" href="http://link.springer.com/search?dc.title=ALAD&facet-content-type=ReferenceWorkEntry&sortOrder=relevance">ALAD</a><span> activityis used as a biomarker and the collection of at least 10 fish ofa species at each site to facilitate statistical analysis.</span></p>
application/pdf
10.1023/A:1015767503629
en
Springer
Inhibition of erythrocytes δ-aminolevulinic acid dehydratase (ALAD) activity in fish from waters affected by lead smelters
article