R. Antipa
D.F. Amend
R. W. Gould
1979
<p><span>Sockeye salmon (</span><i>Oncorhynchus nerka</i><span>) were immersion-vaccinated in suspensions containing 5 × 10</span><sup>7</sup><span>, 5 × 10</span><sup>6</sup><span>, 5 × 10</span><sup>5</sup><span>, or 5 × 10</span><sup>4</sup><span> bacteria/mL of bivalent or monovalent, formalin-killed</span><i>Vibrio anguillarum</i><span>, Types I and II. The fish were split into two lots and held for 54 d. At that time one lot was challenged with living, virulent </span><i>V</i><span>. </span><i>anguillarum</i><span>, Type I, and one with living, virulent </span><i>V</i><span>.</span><i>anguillarum</i><span>, Type II. Immunization with bivalent bacterin effectively protected the fish from vibriosis, but monovalent vaccine was effective only against the homologous challenge. Immunization with the highest concentration of Type I monovalent bacterin resulted in 0% Type I and 58% Type II challenge mortality. Immunization with the highest concentration of Type II monovalent bacterin resulted in 41% Type I and 0% Type II challenge mortality. Immunization with the highest concentration of bivalent Type I/Type II bacterin resulted in 2% mortality in both challenges. Protective bacterins were effective at concentrations down to 5 × 10</span><sup>5</sup><span> bacteria/mL.</span><i>Key words</i><span>: immersion vaccination, bivalent vaccines, </span><i>Vibrio anguillarum</i><span>, vibriosis.</span></p>
application/pdf
10.1139/f79-033
en
NRC Research Press
Immersion vaccination of sockeye salmon (Oncorhynchus nerka) with two pathogenic strains of Vibrio anguillarum
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