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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:contributor>Carol Ann Woody</dc:contributor>
  <dc:contributor>Chris Habicht</dc:contributor>
  <dc:contributor>G. Kevin Sage</dc:contributor>
  <dc:contributor>James E. Seeb</dc:contributor>
  <dc:contributor>Fred W. Allendorf</dc:contributor>
  <dc:creator>Kristina M. Ramstad</dc:creator>
  <dc:date>2007</dc:date>
  <dc:description>&lt;p&gt;&lt;span class="EXLDetailsDisplayVal"&gt;Genetic bottleneck effects can reduce genetic variation, persistence probability, and evolutionary potential of populations. Previous microsatellite analysis suggested a bottleneck associated with a common founding of sock-eye&amp;nbsp;&lt;span class="searchword"&gt;salmon&lt;/span&gt;&amp;nbsp;Oncorhynchus nerka populations of&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;Clark&lt;/span&gt;, Alaska, about 100 to 400 generations ago. The common founding&lt;span class="searchword"&gt;event&lt;/span&gt;&amp;nbsp;occurred after the last glacial recession and resulted in reduced allelic diversity and strong divergence of&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;Clark&lt;/span&gt;&lt;span class="searchword"&gt;sockeye&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;salmon&lt;/span&gt;&amp;nbsp;relative to neighboring Six Mile&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;and&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;Iliamna populations. Here we used two additional genetic marker types (allozymes and mtDNA) to examine these patterns further. Allozyme and mtDNA results were congruent with the microsatellite data in suggesting a common&amp;nbsp;&lt;span class="searchword"&gt;founder&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;event&lt;/span&gt;&amp;nbsp;in&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&lt;span class="searchword"&gt;Clark&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;sockeye&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;salmon&lt;/span&gt;&amp;nbsp;and confirmed the divergence of&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;Clark&lt;/span&gt;populations from neighboring Six Mile&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;and&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;Iliamna populations. The use of multiple marker types provided better understanding of the bottleneck in&amp;nbsp;&lt;span class="searchword"&gt;Lake&lt;/span&gt;&amp;nbsp;&lt;span class="searchword"&gt;Clark&lt;/span&gt;. For example, the Sucker Bay Lake population had an exceptionally severe reduction in allelic diversity at microsatellite loci, but not at mtDNA. This suggests that the reduced microsatellite variation in Sucker Bay Lake fish is due to consistently smaller effective population size than other Lake Clark populations, rather than a more acute or additional bottleneck since founding. Caution is urged in using reduced heterozygosity as a measure of genetic bottleneck effects because stochastic variance among loci resulted in an overall increase in allozyme heterozygosity within bottlenecked Lake Clark populations. However, heterozygosity excess, which assesses heterozygosity relative to allelic variation, detected genetic bottleneck effects in both allozyme and microsatellite loci.&lt;/span&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;/p&gt;</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:language>en</dc:language>
  <dc:publisher>American Fisheries Society</dc:publisher>
  <dc:title>Concordance of nuclear and mitochondrial DNA markers in detecting a founder event in Lake Clark sockeye salmon</dc:title>
  <dc:type>article</dc:type>
</oai_dc:dc>