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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:contributor>Leonard I Wassenaar</dc:contributor>
  <dc:creator>Tyler B. Coplen</dc:creator>
  <dc:date>2015</dc:date>
  <dc:description>&lt;p&gt;Rationale&lt;/p&gt;&lt;p&gt;Although laser absorption spectrometry (LAS) instrumentation is easy to use, its incorporation into laboratory operations is not easy, owing to extensive offline manipulation of comma-separated-values files for outlier detection, between-sample memory correction, nonlinearity (&lt;i&gt;δ&lt;/i&gt;-variation with water amount) correction, drift correction, normalization to VSMOW-SLAP scales, and difficulty in performing long-term QA/QC audits.&lt;/p&gt;&lt;p&gt;Methods&lt;/p&gt;&lt;p&gt;A Microsoft Access relational-database application, LIMS (Laboratory Information Management System) for Lasers 2015, was developed. It automates LAS data corrections and manages clients, projects, samples, instrument-sample lists, and triple-isotope (&lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;17&lt;/sup&gt;O, &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;18&lt;/sup&gt;O, and &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt;H values) instrumental data for liquid-water samples. It enables users to (1) graphically evaluate sample injections for variable water yields and high isotope-delta variance; (2) correct for between-sample carryover, instrumental drift, and &lt;i&gt;δ&lt;/i&gt; nonlinearity; and (3) normalize final results to VSMOW-SLAP scales.&lt;/p&gt;&lt;p&gt;Results&lt;/p&gt;&lt;p&gt;Cost-free LIMS for Lasers 2015 enables users to obtain improved &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;17&lt;/sup&gt;O, &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;18&lt;/sup&gt;O, and &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt;H values with liquid-water LAS instruments, even those with under-performing syringes. For example, LAS &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt;H&lt;sub&gt;VSMOW&lt;/sub&gt; measurements of USGS50 Lake Kyoga (Uganda) water using an under-performing syringe having ±10 % variation in water concentration gave +31.7 ± 1.6 ‰ (2-σ standard deviation), compared with the reference value of +32.8 ± 0.4 ‰, after correction for variation in δ value with water concentration, between-sample memory, and normalization to the VSMOW-SLAP scale.&lt;/p&gt;&lt;p&gt;Conclusions&lt;/p&gt;&lt;p&gt;LIMS for Lasers 2015 enables users to create systematic, well-founded instrument templates, import &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt;H, &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;17&lt;/sup&gt;O, and &lt;i&gt;δ&lt;/i&gt;&lt;sup&gt;18&lt;/sup&gt;O results, evaluate performance with automatic graphical plots, correct for &lt;i&gt;δ&lt;/i&gt; nonlinearity due to variable water concentration, correct for between-sample memory, adjust for drift, perform VSMOW-SLAP normalization, and perform long-term QA/QC audits easily. Published in 2015. This article is a U.S. Government work and is in the public domain in the USA.&lt;/p&gt;</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>10.1002/rcm.7372</dc:identifier>
  <dc:language>en</dc:language>
  <dc:publisher>Wiley</dc:publisher>
  <dc:title>LIMS for Lasers 2015 for achieving long-term accuracy and precision of δ2H, δ17O, and δ18O of waters using laser absorption spectrometry</dc:title>
  <dc:type>article</dc:type>
</oai_dc:dc>