Carol Clarke Matthew Johnson Emily N. Reinke Barnett A. Rattner Steve Hwang Evisabel Craig Anna Lowit Paul Brown Karen L. Davis-Bruno Annabelle Crusan Suzanne Fitzpatrick Jueichuan Kang Robin Levis Donna L. Mendrick Jill Merrill Brian Berridge Warren Casey Nicole Kleinstreuer Harold Watson John D. Gordon 2021 The U.S. Government Accountability Office (GAO) recommended to Congress that federal agencies establish a workgroup through ICCVAM to propose metrics for assessing progress on the development and promotion of alternative methods. This document describes the recommendations of the ICCVAM Metrics Workgroup. application/pdf en U.S. Department of Health and Human Services Measuring U.S. Federal Agency progress toward implementation of alternative methods in toxicity testing reports