David L. Hall Catherine L. Crawford Caren S. Goldberg Erin L. Muths Brent H. Sigafus Thierry Chambert Blake R. Hossack 2023 <div class="abstract-group "><div class="article-section__content en main"><p>Interventions of the host–pathogen dynamics provide strong tests of relationships, yet they are still rarely applied across multiple populations. After American bullfrogs (<i>Rana catesbeiana</i>) invaded a wildlife refuge where federally threatened Chiricahua leopard frogs (<i>R. chiricahuensis</i>) were reintroduced 12 years prior, managers launched a landscape-scale eradication effort to help ensure continued recovery of the native species. We used a before-after-control-impact design and environmental DNA sampling of 19 eradication sites and 18 control sites between fall 2016 and winter 2020–2021 to measure community-level responses to bullfrog eradication, including for two pathogens. Dynamic occupancy models revealed successful eradication from 94% of treatment sites. Native amphibians did not respond to bullfrog eradication, but the pathogens amphibian chytrid fungus (<i>Batrachochytrium dendrobatidis</i>) and ranaviruses were coextirpated with bullfrogs. Our spatially replicated experimental approach provides strong evidence that management of invasive species can simultaneously reduce predation and disease risk for imperiled species.</p></div></div> application/pdf 10.1111/conl.12970 en Wiley Successful eradication of invasive American bullfrogs leads to coextirpation of emerging pathogens article