<?xml version='1.0' encoding='utf-8'?>
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:contributor>Eric Leis</dc:contributor>
  <dc:contributor>Aaron R. Cupp</dc:contributor>
  <dc:contributor>Laura Lynne Peterman</dc:contributor>
  <dc:contributor>Jillian Hebert</dc:contributor>
  <dc:contributor>Richard A. Erickson</dc:contributor>
  <dc:contributor>Susan M. Schleis</dc:contributor>
  <dc:contributor>Mark P. Gaikowski</dc:contributor>
  <dc:creator>Maren T. Tuttle-Lau</dc:creator>
  <dc:date>2023</dc:date>
  <dc:description>&lt;h3 id="aah10179-sec-0051-title" class="article-section__sub-title section1"&gt;Objective&lt;/h3&gt;&lt;p&gt;The ability to effectively treat parasitic infestations of fish is of high importance for fish culture facilities. However, tools or approved therapies for treating infestations on fish are limited. This paper summarizes results from four separate clinical field studies that evaluated the efficacy of hydrogen peroxide (H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;; 35% PEROX-AID) for reducing&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;Gyrodactylus&lt;/i&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;spp. infestation density.&lt;/p&gt;&lt;h3 id="aah10179-sec-0052-title" class="article-section__sub-title section1"&gt;Methods&lt;/h3&gt;&lt;p&gt;Three species of&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;Gyrodactylus&lt;/i&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;were studied (&lt;i&gt;G. salmonis&lt;/i&gt;, hosts: Brook Trout&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;Salvelinus fontinalis&lt;/i&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;and Lake Trout&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;S. namaycush&lt;/i&gt;;&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;G. freemani&lt;/i&gt;, host: Yellow Perch&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;Perca flavescens&lt;/i&gt;;&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;G. hoffmani&lt;/i&gt;, host: Fathead Minnow&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;Pimephales promelas&lt;/i&gt;) before and after the application of immersion H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;therapy.&lt;/p&gt;&lt;h3 id="aah10179-sec-0053-title" class="article-section__sub-title section1"&gt;Result&lt;/h3&gt;&lt;p&gt;Parasite density was significantly reduced for each parasite × host combination to which H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;therapy was applied. Two clinical field studies in salmonids were found to demonstrate substantial effectiveness that enabled 35% PEROX-AID approval.&lt;/p&gt;&lt;h3 id="aah10179-sec-0054-title" class="article-section__sub-title section1"&gt;Conclusion&lt;/h3&gt;&lt;p&gt;Further assessments of&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;i&gt;Gyrodactylus&lt;/i&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;spp. could expand the use of H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;for controlling these parasites in aquaculture. Specifically, H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;was effective at all levels tested (50 or 75 mg H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;/L for 60 min for the Yellow Perch and Fathead Minnow clinical field studies; 100 or 150 mg H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;/L for 30 min regardless of salt pre-treatment for the Brook Trout study; and 100 mg H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;/L for 30 min or 50 mg H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;/L for 60 min for the Lake Trout study).&lt;/p&gt;</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>10.1002/aah.10179</dc:identifier>
  <dc:language>en</dc:language>
  <dc:publisher>American Fisheries Society</dc:publisher>
  <dc:title>Efficacy of hydrogen peroxide to reduce Gyrodactylus species infestation density on four fish species</dc:title>
  <dc:type>article</dc:type>
</oai_dc:dc>