Kathryn P. Huyvaert
Dana L. Winkelman
Eric R. Fetherman
Brian W. Avila
2022
<div class="html-p">Infectious bacterial pathogens are a concern for aquaculture as estimates suggest that billions of US dollars are lost annually in aquaculture due to disease. One of the most prevalent salmonid pathogens is the bacterium<span> </span><span class="html-italic">Flavobacterium psychrophilum</span><span> </span>that causes bacterial coldwater disease. We reviewed the published<span> </span><span class="html-italic">F. psychrophilum</span><span> </span>literature and conducted a Bayesian analysis to examine large-scale patterns in rainbow trout (<span class="html-italic">Oncorhynchus mykiss</span>) mortality associated with laboratory challenge. We incorporated factors that were common across a majority of the laboratory exposure studies and these included bacterial dose, culture time, exposure method, bacterial isolate, experimental duration, and fish weight. The comparison showed that injection as the exposure method produced higher mortality than bath immersion, bacterial isolates differed in their effect on mortality, and bacterial dose has an interactive effect with fish weight and exposure method. Our comparison allows for inference on factors affecting rainbow trout mortality due to exposure to<span> </span><span class="html-italic">F. psychrophilum</span><span> </span>and suggests avenues to further optimize research protocols to better reach study goals.</div><div id="html-keywords"><br></div>
application/pdf
10.3390/pathogens11111318
en
MDPI
Factors affecting post-challenge survival of Flavobacterium psychrophilum in susceptible rainbow trout from the literature
article