Tim Harvey-Samuel Limb Hapairai Hervé Bossin Mona Renee Bellinger Adam E Vorsino 2026 <p><span>Mosquito-borne diseases pose an existential threat to the health, economies, and unique ecosystems of Pacific Island Countries and Territories (PICTs). The remoteness of these islands, combined with the presence of highly competent mosquito vectors, complicates disease surveillance and vector control efforts. In response, the PICTs have become a focal point for the development and application of Genetic BioControl (GBC) technologies designed to break vector-borne disease transmission cycles. However, the application of GBC tools in this region warrants careful consideration of its unique history, including a legacy of colonialism, and challenges associated with logistic hurdles. Through meaningful community engagement and authentic collaborations, drawing from local knowledge, and building local capacity, the sustainable, efficient, and effective deployment of GBC tools may be achieved.</span></p> application/pdf 10.1016/j.cois.2025.101484 en Elsevier Genetic biocontrol strategy considerations for mosquito control in the Pacific Island Countries and Territories article