Development and Application of Health-Based Screening Levels for Use in Water-Quality Assessments

Scientific Investigations Report 2007–5106

U.S. GEOLOGICAL SURVEY
Scientific Investigations Report 2007–5106

Table 3. The most recent USEPA sources of cancer classifications and toxicity data are used in the development of HBSLs.

[USEPA, U.S. Environmental Protection Agency; HBSL, Health-Based Screening Level]

USEPA data sources – the most recent USEPA data source for a given chemical is used for HBSL development	Reference(s)
Integrated Risk Information System database (Office of Research and Development)	(U.S. Environmental Protection Agency, 2006d)
Most recent edition of the “Drinking Water Standards and Health Advisories” document (Office of Water)	(U.S. Environmental Protection Agency, 2006a)
Pesticide Tolerance Reassessment and Reregistration documents (Office of Pesticide Programs (OPP)). Toxicity information is available in the following types of documents: Reregistration Eligibility Decision (RED) Interim Reregistration Eligibility Decision (IRED) Reports on Food Quality Protection Act Tolerance Reassessment Progress and [Interim] Risk Management Decisions (TRED) Risk Assessments in support of RED, IRED, or TRED documents	(Regulations.gov, 2007; U.S. Environmental Protection Agency, 2007)
Most recent edition of “Chemicals Evaluated for Carcinogenic Potential” document (OPP)	(U.S. Environmental Protection Agency, 2006b)
Reference Dose Tracking Report (OPP). All reference dose values from the Reference Dose Tracking Report are verified by OPP’s Science Information Management Branch, Health Effects Division, before using to calculate HBSLs because this report has not been updated since 1997. The OPP data sources listed above take precedence over data from the Reference Dose Tracking Report.	(U.S. Environmental Protection Agency, 1997)