Immunostimulation of antibody-producing cells and humoral antibody to fish bacterins by a biological response modifier
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Abstract
Numbers of splenic antibody-producing cells and humoral antibody titres were elevated during immunization regimes in rainbow trout when the bacterins Yersinia ruckeri or Aeromonas salmonicida O-antigen preparations were mixed with the immunostimulator FK-565. Fish sampled 14 days after injection showed a marked increase in the immune response when doses of 5, 10 or 100 μg of antigen were used. The immunostimulator may aid initial antigen uptake and processing.
Publication type | Article |
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Publication Subtype | Journal Article |
Title | Immunostimulation of antibody-producing cells and humoral antibody to fish bacterins by a biological response modifier |
Series title | Journal of Fish Biology |
DOI | 10.1111/j.1095-8649.1987.tb05298.x |
Volume | 31 |
Issue | Supp A |
Year Published | 1987 |
Language | English |
Publisher | Wiley |
Contributing office(s) | Leetown Science Center |
Description | 5 p. |
First page | 87 |
Last page | 91 |
Google Analytic Metrics | Metrics page |