Characterization of EV-2, a virus isolated from European eels (Anguilla anguilla) with stomatopapilloma
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Abstract
A virus designated EV-2 has been isolated from external tumor tissue and internal organs of European eels (Anguilla anguilla) with stomatopapilloma. It contains RNA and is ether, acid, and temperature labile above 4°C, and concentrated preparations agglutinate chicken and sheep erythrocytes. The addition of actinomycin D during the first 2.75 h of infection inhibits viral replication. As determined in sucrose gradients, the buoyant density of the virus is 1.19 g/cm3. EV-2 has a moderately pleomorphic spherical morphology; its diameter ranges from 80 to 140 nm. The virion has narrow, regularly spaced surface projections about 10 nm long. Replication in FHM cells at 15°C shows new infectivity appearing at 10 h postinfection and reaching a plateau at 20 h. Cytopathic effects consist of cell fusion, syncytia, and irregularly rounded cell masses. Viral antigen was detected in the cytoplasm of infected cells by specific immunofluorescence.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Characterization of EV-2, a virus isolated from European eels (Anguilla anguilla) with stomatopapilloma |
| Series title | Journal of Virology |
| DOI | 10.1128/jvi.30.1.358-364.1979 |
| Volume | 30 |
| Issue | 1 |
| Year Published | 1979 |
| Language | English |
| Publisher | American Society for Microbiology |
| Contributing office(s) | Leetown Science Center |
| Description | 7 p. |
| First page | 358 |
| Last page | 364 |
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