Toxicity and oxidative stress of different forms of organic selenium (Se) and dietary protein in mallard (Anas platyrhynchos) ducklings
FASEB Journal
By: D. Hoffman, G. Heinz, J. Eisemann, and G. Pendleton
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Abstract
High concentrations of Se have been found in aquatic food chains associated with irrigation drainwater and toxicity to fish and wildlife. Earlier studies have compared toxicities of Se as selenite and as seleno-DL-methionine (DL) in mallards. This study compares DL, seleno-L-methionine (L), selenized yeast (Y) and selenized wheat (W). Day-old mallard ducklings received an untreated diet (controls) containing 75% wheat (22% protein) or the same diet containing 15 or 30 ppm Se in the above forms. After 2 weeks blood and liver samples were collected for biochemical assays and Se analysis. All forms of selenium caused significant increases in plasma and hepatic glutathione peroxidase activities. Se as L was the most toxic, resulting in high mortality (64%) and impaired growth (>50%) and the greatest increase in ratio of oxidized to reduced glutathione with 30 ppm in the diet. Se as Y accumulated the least in liver. In a subsequent experiment with 30% dietary protein Se as L was less toxic.
Suggested Citation
Hoffman, D., Heinz, G., Eisemann, J., and Pendleton, G., 1994, Toxicity and oxidative stress of different forms of organic selenium (Se) and dietary protein in mallard (Anas platyrhynchos) ducklings: FASEB Journal, v. 8, no. 4.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Toxicity and oxidative stress of different forms of organic selenium (Se) and dietary protein in mallard (Anas platyrhynchos) ducklings |
| Series title | FASEB Journal |
| Volume | 8 |
| Issue | 4 |
| Year Published | 1994 |
| Language | English |
| Contributing office(s) | Patuxent Wildlife Research Center |
| Description | A435 Abstract 2519 |
| Larger Work Type | Article |
| Larger Work Subtype | Journal Article |
| Larger Work Title | FASEB Journal |
| First page | A435 Abstr |