Evaluation of immunoassay for the determination of pesticides at a large-scale groundwater contamination site
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Abstract
Pesticide concentrations in ground water at Rocky Mountain Arsenal (RMA) near Denver, Colorado, were determined using solid-phase extraction (SPE) gas chromatography/mass spectrometry (GC/MS) procedures and enzyme-linked immunosorbent assay (ELISA) for cyclodiene insecticides and triazine herbicides. Matrix interferences resulted in inconclusive results for some GC/MS analyses due to baseline disturbances and co-elution, but ELISA analyses consistently gave definitive results in a minimum amount of time. ELISA was used initially as a screening method, and pesticide concentrations and plume extents identified by ELISA were confirmed by SPE-GC/MS. A high degree of correlation was seen between results from GC/MS and ELISA methods for the triazine herbicides (correlation coefficient (R2) = 0.99). All areas with high pesticide concentrations were found to be within the boundaries of RMA.
Study Area
Publication type | Article |
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Publication Subtype | Journal Article |
Title | Evaluation of immunoassay for the determination of pesticides at a large-scale groundwater contamination site |
Series title | ACS Symposium Series |
DOI | 10.1021/bk-1997-0657.ch018 |
Volume | 657 |
Year Published | 1996 |
Language | English |
Publisher | ACS Publications |
Description | 13 p. |
First page | 221 |
Last page | 233 |
Country | United States |
State | Colorado |
Other Geospatial | Rocky Mountain Arsenal |
Google Analytic Metrics | Metrics page |