Use of implantable pellets to administer low levels of methyl mercury to fish

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Implantable pellets of methyl mercury chloride were tested in Nile Tilapia (Oreochromis niloticus) to appraise the effectiveness of the method for chronic studies of mercury. Two dosing regimes of 15 and 1.5 grams/CH3HgCl pellet (test 1) and 1 and 0.1 grams/pellet (test 2-3) of methyl mercury chloride were used in three tests. Additional pellets containing only matrix were used as controls. The pellets were inserted into the peritoneal cavity along with a microchip for identification. Three methods of incision closure: sutures and two types of surgical glue, were tested. Pellets used in test one released the dose too fast, resulting in premature death of the fish. Results from test 2 and 3 show blood mercury concentrations over time and tissue levels at necropsy consistent with dose suggesting that this is a viable method of dosing fish.
Publication type Conference Paper
Publication Subtype Conference Paper
Title Use of implantable pellets to administer low levels of methyl mercury to fish
Issue 1364
Year Published 1999
Language English
Publisher ASTM
Publisher location Conshohocken, PA, United States
Larger Work Title ASTM Special Technical Publication
First page 413
Last page 422
Conference Title Proceedings of the 1998 8th Symposium on Environmental Toxicology and Risk Assessment: Standardization of Biomarkers for Endocrine Disruption and Environmental Assessment
Conference Location Atlanta, GA, USA
Conference Date 20 April 1998 through 22 April 1998
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