Use of implantable pellets to administer low levels of methyl mercury to fish
By: B.S. Arnold, C.H. Jagoe, and T. S. Gross
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Abstract
Implantable pellets of methyl mercury chloride were tested in Nile Tilapia (Oreochromis niloticus) to appraise the effectiveness of the method for chronic studies of mercury. Two dosing regimes of 15 and 1.5 grams/CH3HgCl pellet (test 1) and 1 and 0.1 grams/pellet (test 2-3) of methyl mercury chloride were used in three tests. Additional pellets containing only matrix were used as controls. The pellets were inserted into the peritoneal cavity along with a microchip for identification. Three methods of incision closure: sutures and two types of surgical glue, were tested. Pellets used in test one released the dose too fast, resulting in premature death of the fish. Results from test 2 and 3 show blood mercury concentrations over time and tissue levels at necropsy consistent with dose suggesting that this is a viable method of dosing fish.
| Publication type | Conference Paper |
|---|---|
| Publication Subtype | Conference Paper |
| Title | Use of implantable pellets to administer low levels of methyl mercury to fish |
| Issue | 1364 |
| Year Published | 1999 |
| Language | English |
| Publisher | ASTM |
| Publisher location | Conshohocken, PA, United States |
| Larger Work Title | ASTM Special Technical Publication |
| First page | 413 |
| Last page | 422 |
| Conference Title | Proceedings of the 1998 8th Symposium on Environmental Toxicology and Risk Assessment: Standardization of Biomarkers for Endocrine Disruption and Environmental Assessment |
| Conference Location | Atlanta, GA, USA |
| Conference Date | 20 April 1998 through 22 April 1998 |
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