Holocene alluvium of the Pedhicos River around Lefkosia (Nicosia), Cyprus, was studied. Alluvial stratigraphy was found to present serial flood deposits underlying river terraces and an extensive alluvial fan. It was found that the stratigraphy and geomorphology of the alluvium can be interpreted to distinguish not only the effects of climate change, but also land-use change, and the impact of particular engineering works. It was suggested that details of the physical properties of the flood deposit sequences and paleosols can contribute to modeling various geophysical and engineering properties and in predicting response to vertical acceleration during earthquakes.