High doses of corticosteroid suppress resistance to Ichthyophonus in starry flounder
Links
- More information: Publisher Index Page (via DOI)
- Download citation as: RIS | Dublin Core
Abstract
Application of pharmacological doses of the corticosteroid dexamethasone phosphate to starry flounder Platichthys stellatus resulted in a predisposition to clinical ichthyophoniasis and a progression from latent Ichthyophonus infections to patent, histologically identifiable infections. Among Ichthyophonus-challenged starry flounder, the prevalences of clinical infections and histologically identifiable infections were significantly greater in two groups that received dexamethasone (100% and 31%, respectively) than in the respective control groups (8% and 0%). Proliferation of Ichthyophonus infections in corticosteroid-treated groups may have resulted from suppression of the cellular immune response that typically follows corticosteroid application; however, further studies are needed to determine whether these effects occur at lower, physiological concentrations of corticosteroids.
Suggested Citation
Perry, J., Kocan, R.M., Winton, J., Hershberger, P., 2004, High doses of corticosteroid suppress resistance to Ichthyophonus in starry flounder: Journal of Aquatic Animal Health, v. 16, no. 1, p. 45-49, https://doi.org/10.1577/H03-056.1.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | High doses of corticosteroid suppress resistance to Ichthyophonus in starry flounder |
| Series title | Journal of Aquatic Animal Health |
| DOI | 10.1577/H03-056.1 |
| Volume | 16 |
| Issue | 1 |
| Publication Date | March 01, 2004 |
| Year Published | 2004 |
| Language | English |
| Publisher | Taylor & Francis Online |
| Contributing office(s) | Western Fisheries Research Center |
| Description | 5 p. |
| First page | 45 |
| Last page | 49 |
| Online Only (Y/N) | N |
| Additional Online Files (Y/N) | N |