Uptake, elimination, and relative distribution of perchlorate in various tissues of channel catfish
Environmental Science & Technology
By: J. W. Park, C.M. Bradford, J. Rinchard, F. Liu, M. Wages, A. Waters, R.J. Kendall, T.A. Anderson, and C.W. Theodorakis
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Abstract
This study was undertaken to determine the kinetics of uptake and elimination of perchlorate in channel catfish, Ictalurus punctatus. Perchlorate - an oxidizer used in solid fuel rockets, fireworks, and illuminating munitions - has been shown to effect thyroid function, causing hormone disruption and potential perturbations of metabolic activities. For the uptake study, catfish were exposed to 100 mg/L sodium perchlorate for 12 h to 5 d in the laboratory. Perchlorate in tissues was analyzed using ion chromatography. The highest perchlorate concentrations were found in the head and fillet, indicating that these tissues are the most important tissues to analyze when determining perchlorate uptake into large fish. To calculate uptake and elimination rate constants for fillet, gills, G-I tract, liver, and head, fish were exposed to 100 ppm sodium perchlorate for 5 days, and allowed to depurate in clean water for up to 20 days. The animals rapidly eliminated the perchlorate accumulated showing the highest elimination in fillet (Ke = 1.67 day -1) and lowest elimination in liver (Ke = 0.79 day -1). ?? 2007 American Chemical Society.
Suggested Citation
Park, J.W., Bradford, C., Rinchard, J., Liu, F., Wages, M., Waters, A., Kendall, R., Anderson, T., and Theodorakis, C., 2007, Uptake, elimination, and relative distribution of perchlorate in various tissues of channel catfish: Environmental Science & Technology, v. 41, no. 21, p. 7581-7586, https://doi.org/10.1021/es071365n.
ISSN: 1520-5851 (online)
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Uptake, elimination, and relative distribution of perchlorate in various tissues of channel catfish |
| Series title | Environmental Science & Technology |
| DOI | 10.1021/es071365n |
| Volume | 41 |
| Issue | 21 |
| Publication Date | September 22, 2007 |
| Year Published | 2007 |
| Language | English |
| Larger Work Type | Article |
| Larger Work Subtype | Journal Article |
| Larger Work Title | Environmental Science and Technology |
| First page | 7581 |
| Last page | 7586 |