The Committee on Earth Observation Satellites (CEOS) Infrared and Visible Optical Sensors (IVOS) subgroup members established a set of CEOS-endorsed globally distributed reference standard test sites for the postlaunch calibration of space-based optical imaging sensors. This paper discusses the top five African pseudo-invariant sites (Libya 4, Mauritania 1/2, Algeria 3, Libya 1, and Algeria 5) that were identified by the IVOS subgroup. This paper focuses on monitoring the long-term radiometric stability of the Terra Moderate Resolution Imaging Spectroradiometer (MODIS) and the Landsat 7 (L7) Enhanced Thematic Mapper Plus (ETM+) sensors using near-simultaneous and cloud-free image pairs acquired from launch to December 2008 over the five African desert sites. Residual errors and coefficients of determination were also generated to support the quality assessment of the calibration differences between the two sensors. An effort was also made to evaluate the relative stability of these sites for long-term monitoring of the optical sensors. ??2009 IEEE.