During the course of field work in Cabeza Prieta National Wildlife Refuge, southwestern Arizona, in 2003, James Cain and Brian Jansen collected Salvia vaseyi, previously known only from the western edge of the Sonoran Desert in California and Baja California. Our findings indicate this shrub might be more widespread in southwestern Arizona mountains. Salvia vaseyi in Arizona seems to represent a relict population. There are other shrubby Salvia in Arizona, but S. vaseyi is the most xeric-mhabiting species and has the narrowest ecological and geographical range.