Crop biomass is increasingly being measured with surface reflectance data derived from multispectral broadband (MSBB) and hyperspectral narrowband (HNB) space-borne remotely sensed data to increase the accuracy and efficiency of crop yield models used in a wide array of agricultural applications. However, few studies compare the ability of MSBBs versus HNBs to capture crop biomass variability. Therefore, we used standard data mining techniques to identify a set of MSBB data from the IKONOS, GeoEye-1, Landsat ETM+, MODIS, WorldView-2 sensors and compared their performance with HNB data from the EO-1 Hyperion sensor in explaining crop biomass variability of four important field crops (rice, alfalfa, cotton, maize). The analysis employed two-band (ratio) vegetation indices (TBVIs) and multiband (additive) vegetation indices (MBVIs) derived from Singular Value Decomposition (SVD) and stepwise regression. Results demonstrated that HNB-derived TBVIs and MBVIs performed better than MSBB-derived TBVIs and MBVIs on a per crop basis and for the pooled data: overall, HNB TBVIs explained 5–31% greater variability when compared with various MSBB TBVIs; and HNB MBVIs explained 3–33% greater variability when compared with various MSBB MBVIs. The performance of MSBB MBVIs and TBVIs improved mildly, by combining spectral information across multiple sensors involving IKONOS, GeoEye-1, Landsat ETM+, MODIS, and WorldView-2. A number of HNBs that advance crop biomass modeling were determined. Based on the highest factor loadings on the first component of the SVD, the “red-edge” spectral range (700–740 nm) centered at 722 nm (bandwidth = 10 nm) stood out prominently, while five additional and distinct portions of the recorded spectral range (400–2500 nm) centered at 539 nm, 758 nm, 914 nm, 1130 nm, 1320 nm (bandwidth = 10 nm) were also important. The best HNB vegetation indices for crop biomass estimation involved 549 and 752 nm for rice (R² = 0.91); 925 and 1104 nm for alfalfa (R² = 0.81); 722 and 732 nm for cotton (R² = 0.97); and 529 and 895 nm for maize (R² = 0.94). The higher spectral resolution of the EO-1 Hyperion hyperspectral sensor and the ability of users to choose distinct HNBs for improved crop biomass estimation outweigh the benefits that come with higher spatial resolution of MSBBs.