In Response: Biological arguments for selecting effect sizes in ecotoxicological testing—A governmental perspective
Environmental Toxicology and Chemistry
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Abstract
Criticisms of the uses of the no-observed-effect concentration (NOEC) and the lowest-observed-effect concentration (LOEC) and more generally the entire null hypothesis statistical testing scheme are hardly new or unique to the field of ecotoxicology [1-4]. Among the criticisms of NOECs and LOECs is that statistically similar LOECs (in terms of p value) can represent drastically different levels of effect. For instance, my colleagues and I found that a battery of chronic toxicity tests with different species and endpoints yielded LOECs with minimum detectable differences ranging from 3% to 48% reductions from controls [5].
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | In Response: Biological arguments for selecting effect sizes in ecotoxicological testing—A governmental perspective |
| Series title | Environmental Toxicology and Chemistry |
| DOI | 10.1002/etc.3108 |
| Volume | 34 |
| Issue | 11 |
| Publication Date | November 01, 2015 |
| Year Published | 2015 |
| Language | English |
| Publisher | John Wiley and Sonc, Inc. |
| Contributing office(s) | Idaho Water Science Center |
| Description | 3 p. |
| First page | 2440 |
| Last page | 2442 |
| Online Only (Y/N) | N |
| Additional Online Files (Y/N) | N |