Drug metabolism in birds

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Papers published over 100 years since the beginning of the scientific study of drug metabolism in birds were reviewed. Birds were found to be able to accomplish more than 20 general biotransformation reactions in both functionalization and conjugation. Chickens were the primary subject of study but over 30 species of birds were used. Large species differences in drug metabolism exist between birds and mammals as well as between various birds, these differences were mostly quantitative. Qualitative differences were rare. On the whole, drug metabolism studies in birds have been neglected as compared with similar studies on insects and mammals. The uniqueness of birds and the advantages of using birds in drug metabolism studies are discussed. Possible future studies of drug metabolism in birds are recommended.

Publication type Article
Publication Subtype Journal Article
Title Drug metabolism in birds
Series title Pharmacology
DOI 10.1159/000137327
Volume 19
Year Published 1979
Language English
Publisher Karger
Description 5 p.
First page 289
Last page 293
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