Scientists from the U.S. Geological Survey’s Great Lakes Science Center conducted integrated acoustic and mid-water trawl surveys of Lake Huron annually from 2004-2018. The 2018 survey was conducted during September and included transects in Lake Huron’s main basin, Georgian Bay, and North Channel. Mean lake-wide pelagic fish density was 1532 fish/ha and mean pelagic fish biomass was 4151 g/ha in 2018, which represents 128% and 108% of the long-term mean, respectively. Mean lake-wide biomass was 24% lower in 2018 and mean lake-wide fish density was 3.3% lower in 2018 as compared to 2017. Lake-wide density and biomass of small alewife (< 100 mm) increased significantly in 2018 and was due primarily to increased abundance in the western main basin. Lake-wide density of small rainbow smelt (< 90 mm) increased in 2018 and was a result of increased abundance in the eastern main basin, Georgian Bay, and the North Channel. Biomass of large rainbow smelt (> 90 mm) increased in 2018 and was a result of increased biomass in the main basin and Georgian Bay. Density of small bloater (< 120 mm) declined in the western main basin but increased in other regions of Lake Huron. Biomass of large bloater (> 120 mm) remained at levels similar to 2017 in most regions of Lake Huron. Emerald shiner density and biomass increased in 2018 due to increased abundance in the main basin south and main basin west regions. Density and biomass of large cisco (> 200 mm) declined marginally between 2017 and 2018, but cisco biomass and density has shown an increasing trend in the North Channel and Georgian Bay since 2011.