Remote sensing of flow conditions in stream channels could facilitate hydrologic data collection, particularly in large, inaccessible rivers. Previous research has demonstrated the potential to estimate flow velocities in sediment-laden rivers via particle image velocimetry (PIV). In this study, we introduce a new framework for also obtaining bathymetric information: Depths Inferred from Velocities Estimated by Remote Sensing (DIVERS). This approach is based on a flow resistance equation and involves several assumptions: steady, uniform, one-dimensional flow and a direct proportionality between the velocity estimated at a given location and the local water depth, with no lateral transfer of mass or momentum. As an initial case study, we performed PIV and inferred depths from videos acquired from a helicopter hovering at multiple waypoints along a large river in central Alaska. The accuracy of PIV-derived velocities was assessed via comparison to field measurements and the performance of an optimization-based approach to DIVERS specification of roughness