Active traces of the southern Fairweather fault were revealed by light detection and ranging (lidar) and show evidence for transpressional deformation between North America and the Yakutat block in southeast Alaska. We map the Holocene geomorphic expression of tectonic deformation along the southern 30 km of the Fairweather fault, which ruptured in the 1958 moment magnitude 7.8 earthquake. Digital maps of surficial geology, geomorphology, and active faults illustrate both strike-slip and dip-slip deformation styles within a 10°–30° double restraining bend where the southern Fairweather fault steps offshore to the Queen Charlotte fault. We measure offset landforms along the fault and calibrate legacy ¹⁴C data to reassess the rate of Holocene strike-slip motion (≥49 mm/yr), which corroborates published estimates that place most of the plate boundary motion on the Fairweather fault. Our slip-rate estimates allow a component of oblique-reverse motion to be accommodated by contractional structures west of the Fairweather fault consistent with geodetic block models. Stratigraphic and structural relations in hand-dug excavations across two active fault strands provide an incomplete paleoseismic record including evidence for up to six surface ruptures in the past 5600 years, and at least two to four events in the past 810 years. The incomplete record suggests an earthquake recurrence interval of ≥270 years—much longer than intervals <100 years implied by published slip rates and expected earthquake displacements. Our paleoseismic observations and map of active traces of the southern Fairweather fault illustrate the complexity of transpressional deformation and seismic potential along one of Earth's fastest strike-slip plate boundaries.