Because major mineral deposits in north-central Nevada predate significant Basin and Range extension, a detailed understanding of the timing and kinematics of extensional faulting is necessary to place these deposits in their original structural context. The complexity of pre-Cenozoic deformation in northern Nevada makes restoring Basin and Range faulting difficult without locating well-dated, regionally extensive Cenozoic units that can be used to restore slip along normal faults. The goal of this study is to reconstruct extensional faulting in the Shoshone and northern Toiyabe Ranges by using Cenozoic rocks in and around the Caetano caldera, which formed ca. 33.8 Ma during eruption of the Caetano Tuff. The caldera filled with more than 4 km of intracaldera tuff during initial caldera-forming eruptions, and additional sedimentary and volcanic rocks subsequently filled the topographic depression left by the caldera collapse. These rocks are conformable over the interval 34–25 Ma, consistent with little, if any, extension during that time. The 34–25 Ma rocks were later cut by a set of closely spaced (1–3 km) normal faults that accommodated significant extension and foot-wall rotations of 40°–50°. Restored structural cross sections indicate that the present ∼42 km (east-west) width of the Caetano caldera has been extended 110%, resulting in 22 ± 3 km westward translation of the Fish Creek Mountains relative to the southern Cortez Range. Major normal faults mapped within the caldera continue south and north along strike into the surrounding Paleozoic basement rocks; therefore it is likely that parts of surrounding areas are also significantly extended. Miocene (16–12 Ma) sedimentary rocks in the hanging walls of major normal faults include both fluvial/lacustrine facies and coarser alluvial fan deposits. Where exposed, the bases of the Miocene sedimentary sections are in angular conformity with underlying ∼40°E tilted 34–25 Ma volcanic and sedimentary rocks. The distribution, composition, and geometry of these deposits are best explained by accumulation in a set of half-graben basins that formed in response to slip on basin-bounding faults. Extension thus appears to have taken place in the middle Miocene, beginning at or shortly after 16 Ma, and was mostly completed by 10–12 Ma. Fault blocks and basins formed during middle Miocene extension are cut by younger, more widely spaced, high-angle normal faults that began forming more recently than 10–12 Ma. These faults outline the modern basins and ranges in the study area and some have remained active into the Holocene.