The Aleutian subduction zone is one of the most seismically active plate boundaries and the source of several of the world’s largest historic earthquakes. The structural architecture of the subduction zone varies considerably along its length. At the eastern end is a tectonically complex collision zone where the allochthonous Yakutat terrane is moving northwest into mainland Alaska. West of the collision zone a shallow-dipping subducted plate beneath a wide forearc, nearly orthogonal convergence, and a continental-type subduction regime characterizes the eastern part of the subduction zone. In the central part of the subduction zone, convergence becomes increasingly right oblique and the forearc is divided into a series of large clockwise-rotated fault-bounded blocks. Highly oblique convergence and island arc tectonics characterize the western part of the subduction zone. At the extreme western end of the arc, the relative plate motion is nearly pure strike-slip. A series of great subduction earthquakes ruptured most of the 4000-km length of the subduction zone during a period of several decades in the mid 1900s. The majority of these earthquakes broke multiple segments as defined by the large-scale structure of the overriding plate margin and patterns of historic seismicity. Several of these earthquakes generated Pacific-wide tsunamis and significant damage in the southwestern and south-central regions of Alaska. Characterization of previous subduction earthquakes is important in assessing future seismic and tsunami hazards. However, at present such information is available only for the eastern part of the subduction zone. The 1964 Alaska earthquake (M 9.2) ruptured about ~950 km of the plate boundary that encompassed the Kodiak and Prince William Sound (PWS) segments. Within this region, nine paleosubduction earthquakes in the past ~5000 years are recognized on the basis of geologic evidence of sudden land level change and, at some sites, coeval tsunami deposits. Carbon 14-based chronologies indicate recurrence intervals between median calibrated ages for these paleoearthquakes range from 333 to 875 years. The most recent occurred about 489 years ago and broke only the Kodiak segment. During the previous three cycles, both the Kodiak and PWS segments were involved in either multiple-segment ruptures or closely timed pairs of single segment ruptures. evidence for the earlier paleosubduction earthquakes has been found only at sites in the PWS segment. Thus, future work on the paleoseismicity of other segments would by particular valuable in defining the seismic behavior of the subduction zone.