The mitigation of losses due to extreme climate events and long-term climate adaptation requires climate informed decision-making. In the past few decades, several remote sensing and modeled-based Earth observations (EOs) have been developed to provide an unprecedented global overview and routine monitoring of climate and its impacts on vegetation and hydrologic conditions, with the goal of supporting informed decision-making. However, their usage in decision-making is particularly limited in climate-risk vulnerable and in situ data-scarce regions such as sub-Saharan Africa, due to lack of access to EOs. Here, we describe the Early Warning eXplorer (EWX), which was developed to address this crucial limitation and facilitate the application of EOs in decision-making, particularly in the food and water-insecure regions of the world. First, the EWX's core framework, which includes (i) the Viewer, (ii) GeoEngine, and (iii) Support Applications, is described. Then, a comprehensive overview of the Viewer, which is a web-based interface used to access EOs, is provided. This includes a description of (i) the maps and associated features to access gridded EO data and anomalies for different temporal averaging periods, (ii) time series graphs and associated features to access EOs aggregated over polygons such as administrative boundaries, and (iii) commonly used EOs served by the EWX that provide assessments of climate and vegetation conditions. Next, examples are provided to demonstrate how EWX can be used to monitor development, progression, spatial extent, and severity of climate-driven extreme events to support timely decisions related to mitigation of food insecurity and flooding impacts. Finally, the value of a regional implementation of EWX at the Regional Centre for Mapping of Resources for Development (RCMRD) in Nairobi, Kenya, is highlighted. Regional implementation of the EWX facilitates access to regionally focused EOs and their availability at polygon boundaries most relevant to the local decision-makers. Similar instances of EWX implemented in other regions, especially those susceptible to food and water security, will likely further enhance the application of EOs for informed decision-making.