Prion forensics: A multidisciplinary approach to investigate CWD at an illegal deer carcass disposal site

Prion
By: , and 

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Abstract

Infectious prions are resistant to degradation and remain infectious in the environment for several years. Chronic wasting disease (CWD) has been detected in cervids inhabiting North America, the Nordic countries, and South Korea. CWD-prion spread is partially attributed to carcass transport and disposal. We employed a forensic approach to investigate an illegal carcass dump site connected with a CWD-positive herd. We integrated anatomic, genetic, and prion amplification methods to discover CWD-positive remains from six white-tailed deer (Odocoileus virginianus) and, using microsatellite markers, confirmed a portion originated from the CWD-infected herd. This approach provides a foundation for future studies of carcass prion transmission risk.

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Publication type Article
Publication Subtype Journal Article
Title Prion forensics: A multidisciplinary approach to investigate CWD at an illegal deer carcass disposal site
Series title Prion
DOI 10.1080/19336896.2024.2343298
Volume 18
Issue 1
Year Published 2024
Language English
Publisher Taylor & Francis
Contributing office(s) Coop Res Unit Leetown
Description 15 p.
First page 72
Last page 86
Country United States
State Minnesota
County Beltrami County
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