Demographic risk factors vary in the invasion front of chronic wasting disease in West Virginia, USA

Journal of Wildlife Diseases
By: , and 

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Abstract

After detecting chronic wasting disease (CWD) in white-tailed deer (Odocoileus virginianus) in Hampshire County, West Virginia, USA, in 2005, we investigated the change of CWD apparent prevalence and potential factors influencing infection risk during the invasion front. Over eight sampling years (2006–2012 and 2017) during a 12-yr period within a 101-km2-area monitoring zone, we sampled and tested a total of 853 deer for CWD by ELISA and immunohistochemistry. Bayesian logistic regression of risk factors included collection year, age class, sex, and adjusted body weight (weight after accounting for sex, age, kidney fat index, and number of fetuses). In the whole-herd model (n=634), collection year, age, and adjusted body weight were associated with increased odds of CWD, whereas an age-weight interaction had a negative relationship. We found that males drove the positive associations with age and adjusted body weight, whereas females were responsible for the negative interaction effect. These findings suggest potential behavioral and physiological mechanisms related to sex that may influence CWD exposure. Older males exhibited higher CWD prevalence, aligning with previous studies. Notably, the novel finding of adjusted body weight as a risk factor in males warrants further investigation, and this study highlights the need for future research on social behavior and its role in CWD transmission within white-tailed deer populations.

Publication type Article
Publication Subtype Journal Article
Title Demographic risk factors vary in the invasion front of chronic wasting disease in West Virginia, USA
Series title Journal of Wildlife Diseases
DOI 10.7589/JWD-D-22-00160
Volume 60
Issue 4
Year Published 2024
Language English
Publisher BioOne
Contributing office(s) Northern Rocky Mountain Science Center
Description 11 p.
First page 839
Last page 849
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