Understanding human-predator interactions has been a central goal of conservation for decades, yet many previous efforts have approached this challenge from disciplinary perspectives focused on single case studies. There is a need for more transdisciplinary and multi-sited research to enrich our understandings of the complexity of human-nonhuman interactions and to design ways to make them more convivial. The multi-year CONVIVA “convivial conservation” research project addressed this gap, involving scholars from natural sciences, social sciences and humanities to promote coexistence, biodiversity and justice in conservation across four diverse case studies of apex predators: jaguars in Brazil, wolves in Finland, lions in Tanzania, and brown bears in California, United States. In this article, we set out two key contributions. First, we highlight how our project created iterative, dialogue-based reflections amongst different disciplines and perspectives to inform research questions, methods and units of analysis, fulfilling what we see as a key need in the literature. Second, we operationalise our collaboration beyond disciplinary silos into a novel framework of five interconnected dimensions of analysis, that characterise human-predator interactions, drawing on a range of lenses and including a series of guiding questions. We also showcase empirical material from our cases across wildlife, environment, interactions, institutions and justice dimensions. We present our approach, framework and findings with collective reflections and an invitation for adaptation and further research on their suitability to other contexts and species.