The distribution of river-bed grain sizes plays a foundational role in river morphology and ecology. River-bed grain size is a key driver of channel form and process, and has first order effects on aquatic macroinvertebrate assemblages, fish nesting, and biogeochemical processes. Despite this importance, tools to spatially quantify grain-size distributions, particularly submerged grain-size distributions, are lacking. Efforts to address this knowledge gap include developing optical and sonographic tools, however, these approaches have limitations, especially in shallow rivers and over large spatial extents. This study quantifies submerged grain size at high resolution (1 m²) across 260 km of geomorphically diverse river corridors in the Santiam River Basin, Oregon, by pairing bathymetric Lidar point clouds with georeferenced pebble counts. Results suggest that derivatives of Lidar point clouds are able to accurately estimate measured median grain size across seven of the eight river reaches investigated, including reaches above and below high-head dams. Spatial analysis of predicted grain-sizes in the context of Chinook salmon spawning habitat suggests that suitable size sediment patches in the upper, unregulated reaches the study basin is typically small and unorganized. In contrast, the larger rivers downstream of high-head dams typically have larger areas of suitable spawning gravels. This method may be useful for quantification of fish and macroinvertebrates habitats, surface grain-size metrics for sediment transport models, and monitoring of natural and anthropogenic changes in river systems.