Cooling perspectives on the risk of pathogenic viruses from thawing permafrost

mSystems
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Abstract

Climate change is inducing wide-scale permafrost thaw in the Arctic and subarctic, triggering concerns that long-dormant pathogens could reemerge from the thawing ground and initiate epidemics or pandemics. Viruses, as opposed to bacterial pathogens, garner particular interest because outbreaks cannot be controlled with antibiotics, though the effects can be mitigated by vaccines and newer antiviral drugs. To evaluate the potential hazards posed by viral pathogens emerging from thawing permafrost, we review information from a diverse range of disciplines. This includes efforts to recover infectious virus from human remains, studies on disease occurrence in polar animal populations, investigations into viral persistence and infectivity in permafrost, and assessments of human exposure to the enormous viral diversity present in the environment. Based on currently available knowledge, we conclude that the risk posed by viruses from thawing permafrost is no greater than viruses in other environments such as temperate soils and aquatic systems.

Publication type Article
Publication Subtype Journal Article
Title Cooling perspectives on the risk of pathogenic viruses from thawing permafrost
Series title mSystems
DOI 10.1128/msystems.00042-24
Volume 10
Year Published 2025
Language English
Publisher American Society for Microbiology
Contributing office(s) Geology, Minerals, Energy, and Geophysics Science Center
Description e00042-24, 13 p.
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