The timing and failure conditions of an earthquake are governed by the interplay between fault reloading and restrengthening. The moment-recurrence time behavior of repeating earthquakes can give observational estimates of fault healing rates; however, it is difficult to link these observed healing rates to laboratory studies of frictional healing in part because of uncertainty in lithology. Here, we study the 2011 Prague earthquake sequence, which includes repeating earthquakes in the Arbuckle group and the granitic basement, and compare them to laboratory experiments on samples of the Arbuckle and Troy granite (representative of the basement rock) (Okamoto et al., 2025, https://doi.org/10.1029/2024JB030573). We find three spatially distinct groups of repeating earthquakes with different moment-recurrence behavior: (a) constant moment-recurrence time in the Arbuckle group, (b) scattered moment-recurrence time at the intersection of the foreshock-mainshock fault in the granitic basement, and (c) moment-predictable behavior outside of the foreshock-mainshock fault intersection also in the granitic basement. Our observation of stagnant healing for repeating sequences in the Arbuckle group is consistent with laboratory observations of low healing rates for moderately high pore fluid pressures in Arbuckle samples. For the moment-predictable group, the source radius that is required in order to match healing rates is consistent with source radius estimations when taking into account reasonable attenuation of the P-pulse width. Overall, we observe diverse healing behaviors in the seismic families that are consistent with laboratory healing rates, providing seismic evidence that contact-scale frictional mechanisms are relevant to large-scale earthquake dynamics.