Limited favorable weather windows for post-germination early seedling survival are associated with low restoration success in drylands. We examined whether post-fire seeding decisions could alter early seedling emergence and restoration success across western North American sagebrush ecosystems with a simulation approach. Seedling emergence estimates were based on germination of a specified percentile of sown seeds followed by favorable conditions for seedling development. We asked how three categories of seeding decisions affected emergence: post-fire seeding year, seasonal seeding delay (via seed coating technologies or later seeding timing), or native perennial grass seed source (via differing germination behavior). We also tested potential effects of mean annual precipitation on seeding decision outcomes (interactive effect) and included topographic microclimate and site (random effect) in models. Emergence was highest when the best seed source (of 10) was seeded in the best post-fire year (of 5). High emergence also resulted from seeding in the best post-fire year with an average seed source or seeding with the best source in the first post-fire year. Emergence was higher overall with higher mean precipitation. Seeding decision outcomes were sensitive to annual mean precipitation, with greater differences observed due to decisions at lower precipitation levels. While sensitive to assumptions related to seedling development and germination speed, these results suggest that restoration approaches linked to germination behavior and weather variability could improve restoration success rates in variable drylands like sagebrush ecosystems.