A fresh perspective - Advancing fish immunotoxicology in a complex world
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Abstract
Understanding how environmental changes affect the health of organisms and ecosystems is complex, but recent interdisciplinary advances and the recognition of immune function as a dynamic mediator offer exciting progress. Environmental immunotoxicology in teleost fishes is evolving beyond cataloguing stressors towards a mechanistic, integrative framework that leverages omics, in vivo tracking and cross-disciplinary modelling. However, knowledge gaps in immune mechanisms, toxicokinetics and multi-stressor interactions remain. The present work highlights these gaps, advocating for immune function as both a mechanistic lens and an integrative health indicator. Such a framework can improve predictive risk assessments, management strategies and our understanding of contaminant effects on resilience, disease susceptibility and population viability. While challenges remain, the field is poised for significant growth through collaborative innovation and advancing technology.
Suggested Citation
Smith, C.R., Burattin, L., Iglesias, N.R., Sullivan, R., Rice, C.D., Segner, H., Tort, L., 2026, A fresh perspective - Advancing fish immunotoxicology in a complex world: FEBS Letters, 19 p., https://doi.org/10.1002/1873-3468.70296.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | A fresh perspective - Advancing fish immunotoxicology in a complex world |
| Series title | FEBS Letters |
| DOI | 10.1002/1873-3468.70296 |
| Edition | Online First |
| Publication Date | February 04, 2026 |
| Year Published | 2026 |
| Language | English |
| Publisher | FEBS Press |
| Contributing office(s) | Eastern Ecological Science Center |
| Description | 19 p. |