The McCarthy 1? by 3? quadrangle, in eastern south-central Alaska, contains potentially significant resources of copper and possibly of a few other commodities. This circular and a companion folio of maps represent results of integrated field and laboratory studies in the disciplines of geology, geophysics, geochemistry, and satellite imagery that are designed to provide a modern mineral resource assessment of the quadrangle. The maps are accompanied by descriptive texts, explanatory material, pertinent references, and by a few auxiliary tables and diagrams. This circular provides background information for the mineral resource assessment and integrates the component maps. It also includes a master list of references (see 'Bibliography') relevant to the geology and mineral deposits of the quadrangle.