The headwater locations of several thousand U.S. streams tributary to Lakes Ontario and Erie and the St. Lawrence and Niagara Rivers, from the Maumee River in Ohio to the western border of the Lake Champlain basin in New York, including parts of Pennsylvania, are listed by quadrangle. The location of the headwater of each is given with reference to cultural and topographic features. ' Headwater ' in this report is defined as the first site downstream from which the average streamflow is 5 cubic feet per second. The site locations were determined from drainage areas as indicated on topographic maps. The size of the drainage area required to produce an average flow of 5 cubic feet per second was determined from equations, developed separately for each State by regression techniques, that define the relation between streamflow and hydrologic factors of the region. Drainage area and precipitation were factors in the equations for all three States: forest cover was found to be significant in Ohio. (Woodard-USGS)