We present a three-dimensional geologic model of the San Joaquin Basin (SJB) that may be the first compilation of subsurface data spanning the entire basin. The model volume spans 200 × 90 miles, oriented along the basin axis, and extends to ~11 miles depth, for a total of more than 1 million grid nodes. This model supported the 2003 U.S. Geological Survey assessment of future additions to reserves of oil and gas in the SJB. Data sources include well-top picks from more than 3,200 wildcat and production wells, published cross sections, regional seismic grids, and fault maps. The model consists of 15 chronostratigraphic horizons ranging from the Mesozoic crystalline basement to the topographic surface. Many of the model units are hydrocarbon reservoir rocks and three—the Cretaceous Moreno Formation, the Eocene Kreyenhagen Formation, and the Miocene Monterey Formation—are hydrocarbon source rocks. The White Wolf Fault near the southern end of the basin divides the map volume into 2 separate fault blocks. The construction of a three-dimensional model of the entire SJB encountered many challenges, including complex and inconsistent stratigraphic nomenclature, significant facies changes across and along the basin axis, time-transgressive formation tops, uncertain correlation of outcrops with their subsurface equivalents, and contradictory formation top data. Although some areas of the model are better resolved than others, the model facilitated the 2003 resource assessment in several ways, including forming the basis of a petroleum system model and allowing a precise definition of assessment unit volumes.