This 1:50,000-scale map compiles geologic mapping of the Pueblo of Isleta tribal lands and vicinity in the central part of the Albuquerque Basin in central New Mexico. The map synthesizes new geologic mapping and summarizes the stratigraphy, structure, and geomorphology of an area of approximately 2,000 km2 that spans the late Paleogene-Neogene Rio Grande rift south of Albuquerque, N. Mex. The map is part of studies conducted between 1996 and 2001 under the U.S. Geological Survey (USGS) Middle Rio Grande Basin Study by geologists from the USGS, the New Mexico Bureau of Geology and Mineral Resources (NMBGMR), and the University of New Mexico (UNM). This work was conducted in order to investigate the geologic factors that influence ground-water resources of the Middle Rio Grande Basin, and to provide new insights into the complex geologic history of the Rio Grande rift in this region.