Water resources data for the 2001 water year for South Carolina consist of records of stage, discharge, and water quality of streams; stage and contents of lakes and reservoirs; and ground-water levels. This report contains discharge records for 121 gaging stations; stage-only records for 44 gaging stations; stage and co ntents for 14 lakes and reservoirs; water quality for 47 gaging stations; and water levels for 43 observation wells. Als o included are data for 52 crest-stage partial-record stations and discharge measurements at 7 miscellaneous sites. Add itional water data were collected at various sites, not part of the systematic data collection program, and are publish ed as miscellaneous investigations of water quality. These data represent that part of the National Water Data System co llected by the U.S. Geological Survey and cooperating State and Federal agencies in South Carolina.