Experimental propagation of lymphocystis disease of fishes

Virology
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Abstract

The agent of lymphocystis disease has been propagated under laboratory conditions for more than 2 years. Although several hatchery-propagated centrarchids are susceptible, the bluegill (Lepomis macrochirus) is the host of choice because it is most easily maintained. At 12.5° the disease was transmitted by implantation and by injection, but there was no evidence of fish-to-fish spread, nor seasonal change in host susceptibility. The infective agent was clearly demonstrated to be filterable (Millipore HA). It retained infectivity in storage at −20° for almost two years, and its viability after desiccation was confirmed. These facts support its postulated viral nature. The virus was glycerol- and ether-sensitive and did not induce formation of giant lymphocystis cells in monolayer cultures of bluegill ovary cells.

Suggested Citation

Wolf, K., 1962, Experimental propagation of lymphocystis disease of fishes: Virology, v. 18, no. 2, p. 249-256, https://doi.org/10.1016/0042-6822(62)90011-9.

Publication type Article
Publication Subtype Journal Article
Title Experimental propagation of lymphocystis disease of fishes
Series title Virology
DOI 10.1016/0042-6822(62)90011-9
Volume 18
Issue 2
Year Published 1962
Language English
Publisher Elsevier
Contributing office(s) Leetown Science Center
Description 8 p.
First page 249
Last page 256
Additional publication details