Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail
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Abstract
Young Japanese quail (Coturnix japonica) were administered NaF for 16 d either in their diet or by esophageal intubation. Based on the total fluoride ion (Σmg F−) intake over the 16-d experimental period, fluoride administered by intubation was at least six times more toxic than that fed in the diet. Dietary concentrations of 1,000 ppm F− (Σmg F− for 16 d = approx. 144) produced no mortality, whereas intubated doses produced 73% or greater mortality in all groups administered 54 mg F−/kg/d or more (Σmg F− for 16 d ≥ approx. 23 mg). Graphic comparison of the regression of log F− ppm in femurs/mg F− intake showed that fluoride levels in the femurs of quail administered fluoride by intubation were higher than in those administered fluoride in the diet.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail |
| Series title | Environmental Toxicology and Chemistry |
| DOI | 10.1002/etc.5620071006 |
| Volume | 7 |
| Issue | 10 |
| Year Published | 1988 |
| Language | English |
| Publisher | Society of Environmental Toxicology and Chemistry |
| Contributing office(s) | Patuxent Wildlife Research Center |
| Description | 5 p. |
| First page | 841 |
| Last page | 845 |
| Google Analytic Metrics | Metrics page |