Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail
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Abstract
Young Japanese quail (Coturnix japonica) were administered NaF for 16 d either in their diet or by esophageal intubation. Based on the total fluoride ion (Σmg F−) intake over the 16-d experimental period, fluoride administered by intubation was at least six times more toxic than that fed in the diet. Dietary concentrations of 1,000 ppm F− (Σmg F− for 16 d = approx. 144) produced no mortality, whereas intubated doses produced 73% or greater mortality in all groups administered 54 mg F−/kg/d or more (Σmg F− for 16 d ≥ approx. 23 mg). Graphic comparison of the regression of log F− ppm in femurs/mg F− intake showed that fluoride levels in the femurs of quail administered fluoride by intubation were higher than in those administered fluoride in the diet.
Suggested Citation
Fleming, W.J., and Schuler, C., 1988, Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail: Environmental Toxicology and Chemistry, v. 7, no. 10, p. 841-845, https://doi.org/10.1002/etc.5620071006.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail |
| Series title | Environmental Toxicology and Chemistry |
| DOI | 10.1002/etc.5620071006 |
| Volume | 7 |
| Issue | 10 |
| Publication Date | October 01, 1988 |
| Year Published | 1988 |
| Language | English |
| Publisher | Society of Environmental Toxicology and Chemistry |
| Contributing office(s) | Patuxent Wildlife Research Center |
| Description | 5 p. |
| First page | 841 |
| Last page | 845 |