Uptake, metabolism, and elimination of fungicides from coated wheat seeds in Japanese quail (Coturnix japonica)
Journal of Agricultural and Food Chemistry
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Abstract
Pesticides coated to the seed surface potentially pose an ecological risk to granivorous birds that consume incompletely buried or spilled seeds. To assess the toxicokinetics of seeds treated with current-use fungicides, Japanese quail (Coturnix japonica) were orally dosed with commercially coated wheat seeds. Quail were exposed to metalaxyl, tebuconazole, and fludioxonil at either a low (0.07, 0.03, and 0.03 mg/kg body weight) or high dose (0.2, 0.09, and 0.1 mg/kg body weight). Fungicides were rapidly absorbed and distributed to tissues. Tebuconazole was metabolized into t-butylhydroxy-tebuconazole. All compounds were eliminated to below detection limits within 24 h. The high detection frequencies observed in fecal samples potentially offers a noninvasive matrix to monitor pesticide exposure. Summing total body burden across plasma, tissue, and fecal samples, less than 9% of the administered dose was identified as the parent fungicide, demonstrating the importance to monitor both active ingredients and their metabolites in biological samples.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Uptake, metabolism, and elimination of fungicides from coated wheat seeds in Japanese quail (Coturnix japonica) |
| Series title | Journal of Agricultural and Food Chemistry |
| DOI | 10.1021/acs.jafc.9b05668 |
| Volume | 68 |
| Issue | 6 |
| Year Published | 2020 |
| Language | English |
| Publisher | ACS |
| Contributing office(s) | California Water Science Center, Patuxent Wildlife Research Center |
| Description | 11 p. |
| First page | 1514 |
| Last page | 1524 |
| Google Analytic Metrics | Metrics page |