Crossroads of highly pathogenic H5N1: overlap between wild and domestic birds in the Black Sea-Mediterranean impacts global transmission
Nichola J. Hill, Lacy M. Smith, Sabir B. Muzaffar, Jessica L. Nagel, Diann Prosser, Jeffery D. Sullivan, Kyle A. Spragens, Carlos A. DeMattos, Cecilia C. Demattos, Lu’ay El Sayed, Kiraz Erciyas-Yavuz, C. Todd Davis, Joyce Jones, Zoltan Kis, Ruben O. Donis, Scott H. Newman, John Y. Takekawa
2021, Virus Evolution (7)
Understanding transmission dynamics that link wild and domestic animals is a key element of predicting the emergence of infectious disease, an event that has highest likelihood of occurring wherever human livelihoods depend on agriculture and animal trade. Contact between poultry and wild birds is a key driver of the emergence...
Investigation of the 2018 thick-billed murre (Uria lomvia) die-off on St. Lawrence Island rules out food shortage as the cause
Alexis Will, Jean-Baptiste Thiebot, S. Ip, Panguk Shoogukwruk, Morgan Annogiyuk, Akinori Takahashi, Valerie I. Shearn-Bochsler, Mary-Lea Killian, Mia Kim Torchetti, Alexander Kitaysky
2020, Deep Sea Research Part II: Topical Studies in Oceanography (181-182)
Die-offs of seabirds in Alaska have occurred with increased frequency since 2015. In 2018, on St. Lawrence Island, seabirds were reported washing up dead on beaches starting in late May, peaking in June, and continuing until early August. The cause of...
The pathogenesis of a North American H5N2 clade 2.3.4.4 group A highly pathogenic avian influenza virus in surf scoters (Melanitta perspicillata)
Jasmine M. Luczo, Diann Prosser, Mary J. Pantin-Jackwood, Alicia Berlin, Erica Spackman
2020, BMC Veterinary Research (16)
BackgroundAquatic waterfowl, particularly those in the order Anseriformes and Charadriiformes, are the ecological reservoir of avian influenza viruses (AIVs). Dabbling ducks play a recognized role in the maintenance and transmission of AIVs. Furthermore, the pathogenesis of highly pathogenic AIV (HPAIV) in dabbling ducks is well characterized. In contrast, the role of...
Genesis and spread of multiple reassortants during the 2016/2017 H5 avian influenza epidemic in Eurasia
Samantha Lycett, Anne Pohlmann, Christoph Staubach, Valentina Caliendo, Mark Woolhouse, Martin Beer, Thijs Kuiken, The Global Consortium for H5N8 and Related Influenza Viruses, Steven van Borm, Andrew Breed, Francois-Xavier Briand, Ian Brown, Adam Dan, Thomas J. DeLiberto, Sophie von Dobschuetz, Ron A. M. Fouchier, Marius Gilbert, Sarah Hill, Charlotte Kristiane Hjulsager, S. Ip, Marion Koopmans, Lars Erik Larsen, Dong-Hun Lee, Mahmoud Mohamed Naguib, I. Monne, Oliver Pybus, Andrew M. Ramey, Vladmir Savic, Kirill Sharshov, Alexander Shestopalov, Chang-Seon Song, Mieke Steensels, David Swayne, Edyta Swieton, Xiu-Feng Wan, Siamak Zohari
Peter Palese, editor(s)
2020, PNAS (117) 20814-20825
Highly pathogenic avian influenza (HPAI) viruses of the H5 A/goose/Guangdong/1/96 lineage can cause severe disease in poultry and wild birds, and occasionally in humans. In recent years, H5 HPAI viruses of this lineage infecting poultry in Asia have spilled over into wild birds and spread via bird migration to countries...
Emerging diseases of avian wildlife
Susan J Tyson-Pello, Glenn H. Olsen
2020, Veterinary Clinics of North America: Exotic Animal Practice (23) 383-395
Climate change and the interaction with humans and domestic species influences disease in avian wildlife. This article provides updated information on emerging disease conditions such as the spread of an Asian tick, Haemaphysalis longicornis, and its associated diseases among migratory birds in the eastern United States; lymphoproliferative disease virus in...
Ecology of influenza A viruses in wild birds and wetlands of Alaska
Andrew M. Ramey, Andrew B. Reeves
2020, Avian Diseases (64) 109-122
Alaska represents a globally important region for the ecology of avian-origin influenza A viruses (IAVs) given expansive wetlands in this region which serve as habitat for numerous hosts of IAVs that disperse among four continents during the annual cycle. Extensive sampling of wild birds for IAVs in Alaska since...
Waterfowl occurrence and residence time as indicators of H5 and H7 avian influenza in North American Poultry
John M. Humphreys, Andy Ramey, David C. Douglas, Jennifer M. Mullinax, Catherine Soos, Paul T. Link, Patrick Walther, Diann J. Prosser
2020, Scientific Reports (10) 16
Avian influenza (AI) affects wild aquatic birds and poses hazards to human health, food security, and wildlife conservation globally. Accordingly, there is a recognized need for new methods and tools to help quantify the dynamic interaction between wild bird hosts and commercial poultry. Using satellite-marked waterfowl, we applied Bayesian...
Field-based method for assessing duration of infectivity for influenza A viruses in the environment
Andrew B. Reeves, Andrew M. Ramey, Joshua C. Koch, Rebecca L. Poulson, David E. Stallknecht
2020, Journal of Virological Methods (277)
Understanding influenza A virus (IAV) persistence in wetlands is limited by a paucity of field studies relating to the maintenance of infectivity over time. The duration of IAV infectivity in water has been assessed under variable laboratory conditions, but results are difficult to translate to more complex field conditions. We...
Limited detection of antibodies to clade 2.3.4.4 A/Goose/Guangdong/1/1996 lineage highly pathogenic H5 avian influenza virus in North American waterfowl
David E. Stallknecht, Clara Kienzle-Dean, Nick Davis-Fields, Christopher S. Jennelle, Andrew S. Bowman, Jacqueline M. Nolting, Walter Boyce, James Crum, Jefferson Santos, Justin D. Brown, Diann Prosser, Susan E.W. De La Cruz, Joshua T. Ackerman, Michael L. Casazza, Scott Krauss, Daniel Perez, Andrew M. Ramey, Rebecca L. Poulson
2019, Journal of Wildlife Diseases (56) 47-57
During 2014, highly pathogenic (HP) influenza A viruses (IAVs) of the A/Goose/Guangdong/1/1996 lineage (GsGD-HP-H5), originating from Asia, were detected in domestic poultry and wild birds in Canada and the US. These clade 2.3.4.4 GsGD-HP-H5 viruses included reassortants possessing North American lineage gene segments; were detected in wild birds in the...
Inactivation of viable surrogates for the select agents virulent Newcastle disease virus and highly pathogenic avian influenza virus using either commercial lysis buffer or heat
Katrina E. Alger, S. Ip, Jeffrey S. Hall, Sean Nashold, Katherine Richgels, Carrie Alison Smith
2019, Applied Biosafety (24) 189-199
Introduction:Federal Select Agent Program regulations require laboratories to document a validated procedure for inactivating select agents prior to movement outside registered space. Avian influenza viruses and virulent Newcastle disease virus (vNDV) are cultured in chicken amnio-allantoic fluid (AAF), but the efficacy of commercial lysis buffers to...
Avian influenza virus prevalence in marine birds is dependent on ocean temperatures
Jeffrey S. Hall, Robert J. Dusek, Sean Nashold, Joshua L. TeSlaa, Bradford R. Allen, Daniel A. Grear
2019, Ecological Applications (30)
Waterfowl and shorebirds are the primary hosts of influenza A virus (IAV), however, in most surveillance efforts, large populations of birds are not routinely examined; specifically marine ducks and other birds that reside predominately on or near the ocean. We conducted a long-term study sampling sea ducks and gulls in...
Epidemic growth rates and host movement patterns shape management performance for pathogen spillover at the wildlife-livestock interface
K.R. Manlove, L. Sam, B. Borremans, E. Frances Cassirer, R. S. Miller, K. Pepin, T. E. Besser, Paul Cross
2019, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences (374)
Managing pathogen spillover at the wildlife–livestock interface is a key step towards improving global animal health, food security and wildlife conservation. However, predicting the effectiveness of management actions across host–pathogen systems with different life histories is an on-going challenge since data on intervention effectiveness are expensive to collect and results...
Artificial intelligence and avian influenza: Using machine learning to enhance active surveillance for avian influenza viruses
Daniel P. Walsh, Ting Fung Ma, S. Ip, Jun Zhu
2019, Transboundary and Emerging Diseases (66) 2537-2545
Influenza A viruses are one of the most significant viral groups globally with substantial impacts on human, domestic animal and wildlife health. Wild birds are the natural reservoirs for these viruses, and active surveillance within wild bird populations provides critical information about viral evolution forming the basis of risk assessments...
The pathogenesis of H7 highly pathogenic avian influenza viruses in Lesser Scaup (Aythya affinis)
Christopher B. Stephens, Diann Prosser, Mary J. Pantin-Jackwood, Alicia Berlin, Erica Spackman
2019, Avian Diseases (63) 230-234
Waterfowl are the natural hosts of avian influenza virus (AIV), and through migration spread the virus worldwide. Most AIVs carried by wild waterfowl are low pathogenic strains; however, Goose/Guangdong/1996 lineage clade 2.3.4.4 H5 highly pathogenic (HP) AIV now appears to be endemic in wild birds in much of...
Aerosol transmission of gull-origin Iceland subtype H10N7 influenza A virus in ferrets
Minhui Guan, Jeffrey S. Hall, Xiaojian Zhang, Robert J. Dusek, Alicia K. Olivier, Liyuan Liu, Lei Li, Scott Krauss, Angea Danner, Tao Li, Wiriya Rutvisuttinunt, Xiaoxu Lin, Gunnar T. Hallgrimsson, Sunna B. Ragnarsdottir, Solvi R. Vignisson, Josh TeSlaa, Sean Nashold, Richard Jarman, Xiu-Feng Wan
2019, Journal of Virology (93)
Subtype H10 influenza A viruses (IAVs) have been recovered from domestic poultry and various aquatic bird species, and sporadic transmission of these IAVs from avian species to mammals (i.e., human, seal, and mink) are well documented. In 2015, we isolated four H10N7 viruses from gulls in Iceland. Genomic analyses showed...
Serologic evidence for influenza A virus exposure in three loon species (Gavia spp.) breeding in Alaska
Brian D. Uher-Koch, Timothy J. Spivey, Caroline R. Van Hemert, Joel A. Schmutz, Kaijun Jiang, Xiu-Feng Wan, Andrew M. Ramey
2019, Journal of Wildlife Diseases (55) 862-867
Limited information exists about exposure to influenza A viruses (IAVs) in many wild waterbird species, including loons. We analyzed serum samples from breeding adult Pacific (Gavia pacifica), Red-throated (Gavia stellata), and Yellow-billed (Gavia adamsii) loons sampled at three locations along the coast of Alaska, US from 2008 to 2017 to...
Influenza A prevalence and subtype diversity in migrating teal sampled along the United States Gulf Coast
Deborah Carter, Paul T. Link, Patrick Walther, Andrew M. Ramey, David E. Stallknecht, Rebecca L. Poulson
2019, Avian Diseases (63) 165-171
Wild birds in the order Anseriformes are important reservoirs for influenza A viruses (IAV); however, IAV prevalence and subtype diversity may vary by season, even at the same location. To better understand the ecology of IAV during waterfowl migration through the Gulf Coast of the United States (Louisiana and Texas),...
Lethal infection of wild raptors with highly pathogenic avian influenza H5N8 and H5N2 viruses in the USA, 2014–15
Susan Knowles, Valerie I. Shearn-Bochsler, S. Ip
2019, Journal of Wildlife Diseases (55) 164-168
An outbreak of highly pathogenic avian influenza (HPAI) led to heavy losses of poultry in commercial farms in North America in 2014–15. Enhanced surveillance by virologists and pathologists at the US Geological Survey National Wildlife Health Center and its partners resulted in the identification of lethal infections with clade 2.3.4.4...
Clade 2.3.4.4 H5 North American highly pathogenic avian influenza viruses infect, but do not cause clinical signs in American Black Ducks (Anas rubripes)
Erica Spackman, Diann Prosser, Mary Pantin-Jackwood, Christopher B. Stephens, Alicia Berlin
2019, Avian Diseases (63) 366-370
Highly pathogenic avian influenza virus (HPAIV) from the goose/Guangdong/1996 clade 2.3.4.4 H5 lineage spread from Asia into North America in 2014, most likely by wild bird migrations. Although several variants of the virus were detected, an H5N8 and H5N2 were the most widespread in North American wild birds and...
Waterfowl spring migratory behavior and avian influenza transmission risk in the changing landscape of the East Asian-Australasian Flyway
Jeffery D. Sullivan, John Y. Takekawa, Kyle A. Spragens, Scott H. Newman, Xiangming Xiao, Paul J. Leader, Bena Smith, Diann J. Prosser
2018, Frontiers in Ecology and Evolution (6) 1-14
Avian influenza has advanced from a regional concern to a global health issue with significant economic, trade, and public health implications. Wild birds, particularly waterfowl (Anseriformes), are known reservoirs for low-pathogenic avian influenza viruses (AIV) and recent studies have shown their potential in the spread of highly pathogenic forms of...
The impact of surveillance and control on highly pathogenic avian influenza outbreaks in poultry in Dhaka division, Bangladesh
Edward Hill, Thomas House, Madhur S. Dhingra, Wantanee Kalpradvidh, Subhash Morzaria, Muzaffar G. Osmani, Eric Brum, Mat Yamage, A. Kalam, Diann J. Prosser, John Y. Takekawa, Xiangming Xiao, Marius Gilbert, Michael J. Tildesley
2018, PLOS Computational Biology (14)
In Bangladesh, the poultry industry is an economically and socially important sector, but it is persistently threatened by the effects of H5N1 highly pathogenic avian influenza. Thus, identifying the optimal control policy in response to an emerging disease outbreak is a key challenge for policy-makers. To inform this aim, a...
Genetic evidence supports sporadic and independent introductions of subtype H5 low pathogenic avian influenza A viruses from wild birds to domestic poultry in North America
Lei Li, Andrew S. Bowman, Thomas J. DeLiberto, Mary L. Killian, Scott Krauss, Jacqueline M. Nolting, Mia Kim Torchetti, Andrew M. Ramey, Andrew B. Reeves, David E. Stallknecht, Richard J. Webby, Xiu-Feng Wan
2018, Journal of Virology (92) 1-16
Wild bird–origin influenza A viruses (IAVs or avian influenza) have led to sporadic outbreaks among domestic poultry in the United States (US) and Canada, resulting in economic losses through the implementation of costly containment practices and destruction of birds. We used evolutionary analyses of virus sequence data to determine that...
Prepublication communication of research results
M. J. Adams, Reid N. Harris, Evan H. Campbell Grant, Matthew J. Gray, M. Camille Hopkins, Samuel A. Iverson, Robert Likens, Mark Mandica, D.H. Olson, Alex Shepack, Hardin Waddle
2018, EcoHealth (15) 478-481
Publishing of scientific findings is central to the scientific process, and it is traditional to consider findings “provisional” until accepted by a peer-reviewed journal. Until publication, communication of provisional findings beyond participants in the study is typically limited. This practice helps assure scientific integrity. However, a dilemma arises when a...
A method for determining avian influenza virus hemagglutinin and neuraminidase subtype association
Christopher Ottinger, Deborah D. Iwanowicz, Luke R. Iwanowicz, Cynthia R. Adams, Lakyn R. Sanders, Christine L. Densmore
2018, Open-File Report 2018-1102
Methods for grouping specific avian influenza virus (AIV) hemagglutinin (HA) and neuraminidase (NA) subtype reverse-transcription polymerase chain reaction (RT-PCR) products into HA:NA subtypes when egg incubation is technically not feasible were evaluated. These approaches were adopted for use as post hoc methods after melt curve analysis. The methods are based...
The aerosphere as a network connector of organisms and their diseases
Jeremy D. Ross, Eli S. Bridge, Diann J. Prosser, John Y. Takekawa
2018, Book chapter, Aeroecology
Aeroecological processes, especially powered flight of animals, can rapidly connect biological communities across the globe. This can have profound consequences for evolutionary diversification, energy and nutrient transfers, and the spread of infectious diseases. The latter is of particular consequence for human populations, since migratory birds are known to host diseases...
